TAMH: A Useful In Vitro Model for Assessing Hepatotoxic Mechanisms
نویسندگان
چکیده
منابع مشابه
TAMH: A Useful In Vitro Model for Assessing Hepatotoxic Mechanisms
In vitro models for hepatotoxicity can be useful tools to predict in vivo responses. In this review, we discuss the use of the transforming growth factor-α transgenic mouse hepatocyte (TAMH) cell line, which is an attractive model to study drug-induced liver injury due to its ability to retain a stable phenotype and express drug-metabolizing enzymes. Hepatotoxicity involves damage to the liver ...
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ژورنال
عنوان ژورنال: BioMed Research International
سال: 2016
ISSN: 2314-6133,2314-6141
DOI: 10.1155/2016/4780872